Standardize matched bacteriophage therapy and quality-controlled manufacturing
#00394
Develop regulated phage libraries, rapid bacterial matching, stable manufacturing, and adaptive treatment protocols for infections that lack effective antibiotic options.
Brussels, Belgium
FailedPhagoBurn consortium and participating European burn centres · Region
PhagoBurn was a randomized, controlled phase 1/2 trial comparing a topical anti-Pseudomonas aeruginosa phage cocktail with standard care for infected burn wounds, conducted across multiple European burn units. Manufactu…
Median time to sustained reduction in bacterial burden47 hours with standard care → 144 hours with phage treatmenthours
Analysable participants with maximal bacterial burden2 of 13 with standard care → 6 of 12 with phage treatmentparticipants
2 sources