Guarantee the market: pooled procurement, subsidy, prequalification and regional manufacturing
#00137
Stabilise antivenom supply with guaranteed-volume pooled procurement, donor/government subsidy, WHO prequalification, and regional manufacturing — so effective, region-matched antivenom stays commercially viable and reaches clinics affordably.
EchiTAb Study Group; MicroPharm (UK) and Instituto Clodomiro Picado (Costa Rica); Nigerian health services · since 2005 · National
A counter-example to the FAV-Afrique collapse: effective, region-matched African antivenom developed and sustained through public-academic partnership rather than a purely commercial market. EchiTAb-G (ovine, monospecif…
Permanent restoration of blood coagulability 6h after 1 vial EchiTAb-G (Kaltungo pre-trial use, 2005)incoagulable blood on presentation146/182 patients (80%, 95% CI 74-85%)
1 source
Sub-Saharan Africa
FailedSanofi Pasteur (manufacturer) · until 2016 · Region
FAV-Afrique was a polyvalent antivenom covering ~10 snake species across sub-Saharan Africa, considered safe and effective. Sanofi Pasteur halted production in 2010 (last batch made 2014, expired June 2016) after sales…
Price per dose>US$100USD
Annual sales vs. disease burden by 2010fell to under 1% of burden (~3,000 cases treated)
$100 · 3 sources