Antibiotic-resistant bacterial infections make common treatment increasingly unreliable
#00365
People worldwide face bacterial infections that no longer respond to available antibiotics, increasing treatment failure, severe illness, deaths and the risks of routine medical care.
#00372The antibiotic development and commercialization system fails to deliver needed treatments
Scientific risk, weak commercial returns and unequal market access leave too few innovative antibiotics for priority resistant pathogens and limit delivery after approval.
#00366Antibiotics are often prescribed, dispensed or used unnecessarily or too broadly
Patients receive antibiotics when not needed, or receive unnecessarily broad, long, or poorly selected treatment, increasing avoidable selection pressure and adverse effects.
#00371AMR surveillance and national action remain fragmented and underfunded
Countries lack complete, comparable, and sustainably financed systems connecting antibiotic use, resistance, policy, and outcomes across human, animal, and environmental health.
#00370Antibiotic residues and resistant organisms contaminate water and soil
Waste from pharmaceutical manufacturing, healthcare, households, farms and sewage systems releases antibiotics, resistant bacteria and resistance genes into environmental reservoirs.
#00369Antimicrobial use in food production selects and spreads resistant bacteria
Routine and poorly controlled antimicrobial use in livestock and aquaculture selects resistant bacteria that can spread through animals, food, workers, waste and the environment.
#00367Resistant bacteria spread through healthcare facilities and communities
Patients and communities are exposed to resistant bacteria through preventable transmission, particularly where infection prevention, sanitation, isolation, and outbreak coordination are weak.
#00368Patients lack timely diagnosis and access to effective antibiotics
Many patients, especially in resource-limited settings, cannot obtain timely microbiology, susceptibility testing, or the effective antibiotics needed to treat resistant infections.